Daily changes in the melatonin content of membranes, cytosol, mitochondria, and nuclei from rat liver of sham-operated (SPx) and pinealectomized (Px) rats. Animals were maintained in a 12:12 h cycle and killed at the indicated hours. Black bar indicates the night period. *p < 0.05, **p < 0.01, and ***p < 0.001 vs. SPx