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. 2014 Feb 20;71(16):2997–3025. doi: 10.1007/s00018-014-1579-2

Table 2.

Melatonin levels in human biological fluids (when available)

Fluid Melatonin (pg/ml) Species References
Cerebrospinal fluid 1.47–542 Human [74]
Bile 2,000–11,000 Pig, rat, guinea pig, rabbit, human, monkey [199]
Follicular fluid

36.5 ± 4.8

12.4–23.8

Human

Human

[245]

[246]

Amniotic fluid (labor) 25–158 Human [301]
Saliva 11–63 Human [296, 297]
Synovial fluid (RA) 79.8 ± 38.9 Human [299]
Breast milk (night) 36–99 Human [305, 307, 308]
Anterior chamber of lens 28–70* Rabbit [143]

References include only those related to the original report of melatonin in a given fluid; more information in the text

RA rheumatoid arthritis

* Expressed in pg/lens