Table 4.
Therapeutic potential examples for particular snake toxin families
| Toxin | Toxin family | Species | Function | Receptor/target | Reference |
|---|---|---|---|---|---|
| TNP-c | Natriuretic peptides | O. microlepidotus | Congestive heart failure | NPR-A | [21] |
| Crotamine | β-Defensins | C. d. terrificus | Cationic probe/molecule delivery | Cell/nucleus | [72] |
| Textlinin-1 (Q8008) | Kunitz peptides | P. textilis | Perioperative bleeding | Plasmin | [89] |
| Omwaprin | Waprins | O. microlepidotus | Antibacterial | Gram +ve bacteria | [95] |
| α-Bungarotoxin | Neurotoxic 3FTxs | B. multicinctus | Muscle and neuronal AChR | α1, α7 AChR | [190] |
| β-Cardiotoxin CTX27 | Cytotoxic 3FTxs | O. hannah | β-Adrenergic receptor blockers-heart failure | β-adrenergic receptor | [131] |
| Contortrostatin | Disintegrins | A. c. contortrix | Tumour growth, angiogenesis, metastasis | αIIbβ3, αVβ3, αVβ5, α5β1 integrins | [191] |
| Crotoxin | PLA2s | C. d. terrificus | Anti-inflammatory, anti-microbial, anti-tumour, analgesic | Multiple targets | [184] |