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. 2013 Aug 3;71(3):467–478. doi: 10.1007/s00018-013-1437-7

Fig. 3.

Fig. 3

Model of the evolution of B-located pseudogenes. The B chromosome descends from A chromosome(s) after spontaneous whole or partial genome duplication. Proto-B still shows sequence similarity to the parental A chromosome(s). A proposed gene dosage compensation mechanism suppresses activity of B-located genes. Finally, B-located gene sequences became pseudogenized by mutations and accumulation of mobile and satellite DNA