Fig. 3.

EG-VEGF effect on HLX expression in PEX and in BeWos. a Effect of HLX inactivation on BeWo proliferation. b, c Effect of EG-VEGF on HLX mRNA expression in PEX cells and in BeWo, respectively. d Depiction of EG-VEGF concentration-dependent (5–100 ng/ml) rescue of proliferation of BeWo cells in the presence of HLX inactivation using siRNA. Data are expressed as mean ± SEM. ^§§Corresponds to the comparison between the control and the HLXsiRNA in the absence of EG-VEGF. *Represents the comparison between the HLXsiRNA in the absence and in the presence of EG-VEGF (50 and 100 ng/ml). ^ns Corresponds to the comparison between the HLXsiRNA in the absence and in the presence of EG-VEGF (5–25 ng/ml) (*p < 0.05, **p < 0.01 vs. control)