Table 1.
| Human diseases | Connexins |
|---|---|
| X-linked Charcot–Marie–Tooth disease (CMTX) | Cx32 |
| Atrial fibrillation | Cx40 |
| Viscero-atrial heterotaxia | Cx43 |
| Cataract | Cx46, Cx50 |
| Oculodentodigital dysplasia (ODDD) | Cx43 |
| Clouston syndrome | Cx30 |
| Hearing loss (non-syndromic or associated with skin | Cx26, Cx30, Cx31 |
| Keratitis ichthyosis deafness syndrome | Cx26, Cx30 |
| Erythrokeratodermia variabilis | Cx30.3, Cx31 |
| Pelizaeus–Merzbacher-like | Cx46.6, Cx47 |
| Vohwinkel syndrome | Cx26 |
| Human cancers | Connexins |
|---|---|
| Head and neck carcinoma | Cx31.1 |
| Nasopharyngeal carcinoma | Cx43, Cx45 |
| Meningioma and hemangiopericytoma | Cx26, Cx43 |
| Human larynx carcinoma | Cx26, Cx30, Cx32, Cx40 |
| Liver tumor | Cx32, Cx43 |
| Colon cancer | Cx26, Cx43 |
| Esophageal cancer | Cx26, Cx32, Cx43 |
| Breast cancer | Cx26, Cx43 |
| Mesothelioma tumor | Cx37, Cx43, Cx45 |
| Glioblastoma | Cx43 |
| Lung cancer | Cx43 |
| Adrenocortical tumors | Cx43 |
| Renal cell cancer | Cx32, Cx43 |
| Cervical carcinoma | Cx43 |
| Ovarian carcinoma | Cx43 |
| Endometrial carcinoma | Cx43 |
| Prostate tumor | Cx26, Cx32, Cx43 |
| Bladder cancer | Cx26 |
| Thyroid carcinoma | Cx26, Cx32, Cx43 |
| Testis cancer | Cx26, Cx40, Cx43 |
| Hepatocarcinogenesis | Cx26, Cx32 |
| Skin tumor | Cx26, Cx30 |