Fig. 2.
Probe trial performance in the radial arm water maze problem solving task of PLB1Triple and PLB1WT mice. Both genotypes showed a statistically significant preference for the target arm at 4, 8 and 12 months of age as also indicated by the representative swim paths given below (target arm indicated as grey underlay). In the 12 month group, PLB1WT mice spent longer in the target arm than their transgenic counterparts. Group means + SEM. *p < 0.05 and ***p < 0.001, respectively