EW-7197 ameliorates collagen accumulation in fibrotic tissue. a–d Masson’s trichrome staining (upper), western blot (lower left), and qRT-PCR (lower right) analysis of collagen in liver tissues of CCl4 mice (a), BDL rats (b), UUO mice (c), and BLM mice (d). GAPDH was used as a reference. *p < 0.05 vs. Sham, **p < 0.01 vs. Sham, ***p < 0.001 vs. Sham, #
p < 0.05 vs. Vehicle, ##
p < 0.01 vs. Vehicle, ###
p < 0.001 vs. Vehicle. Scale bars 100 μm