Fig. 1.

Nervous system function behavioral test. a Morris water maze acquisition trials on 84-week-old mice. Average time to find a hidden platform was measured, indicating the third acquisition time differed significantly in the control and biopsied mice (biopsy n = 37, control n = 15, *p < 0.01). b Pole climbing test on 83-week-old mice. Times until the mouse turned its head downwards and touched the floor with its front claw were measured; no significant differences were observed between the biopsied and control groups (biopsy n = 7, control n = 10, p > 0.05)