Table 1.

The genes containing differentially methylated loci in promoter regions in adult biopsied and control mice

Gene name	Annotation	Methylation pattern in biopsied mice
Ireb2	Alzheimer’s disease; resembling Parkinson’s disease	Hypomethylation
Acsm1	Schizophrenia	Hypermethylation
Chd4	Peripheral nerve myelination	Hypomethylation
Kcne2	Neuronal excitability; schizophrenia	Hypermethylation
Gm239	Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder.	Hypermethylation
Wbscr22	Williams-Beuren syndrome (WBS) (mental retardation, unique cognitive and personal profiles)	Hypermethylation
Plunc	Mycoplasma infection and allergic inflammation	Hypomethylation
Tslp	Inflammation and gastrointestinal allergy	Hypermethylation
Dnd1	Germ cell development	Hypermethylation
Prm1	Spermatogenesis and spermatid development	Hypermethylation
Cma2	Generation and degradation of Ang II	Hypomethylation