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. 2024 May 8;42(5):487–493. [Article in Chinese] doi: 10.3724/SP.J.1123.2023.12020

表1.

10组PBL项目

Nos. Project (Title) Score (×coefficient)
1-7 Based on the structure and properties of select compounds, two methods (at least one of which is a chromatographic method) for identification and one chromatographic method for content determination should be designed by referring to the literature and combining previous knowledge. The structural formulas are as follows:
Inline graphic
100 (×0.9)
8 An HPLC fingerprint analysis scheme should be designed to analyze the active components of a Chinese medicine without obvious UV absorption. 100 (×1.0)
9 An HPLC scheme should be designed for the qualitative and quantitative analyses of five anthraquinones in Rheum palmatum L. (rhein, emodin, chrysophanol, physcion, and aloe-emodin). 100 (×1.0)
10 A chromatography-based method, together with a sample-pretreatment method, should be designed to enable the study of the metabolism of phenobarbital in mouse blood. 100 (×1.0)