TABLE 1.
Participant characteristics
| Parameter | AD‐P | AD+P | Total | |||
|---|---|---|---|---|---|---|
| N (%) or mean (SD) | N (%) or mean (SD) | N (%) or mean (SD) | ||||
| 6027 (60.3%) | 3961 (39.7) | 9988 (100.0%) | ||||
| AD‐A | AD+A | AD‐A | AD+A | AD‐A | AD+A | |
| N (%) or mean (SD) | N (%) or mean (SD) | N (%) or mean (SD) | N (%) or mean (SD) | N (%) or mean (SD) | N (%) or mean (SD) | |
| 3199 (53.1) | 2828 (46.9) | 1183 (29.9) | 2778 (70.1) | 4382 (43.9) | 5606 (56.1) | |
| Female | 1810 (56.6) | 1677 (59.3) | 781 (66.0) | 1817 (65.4) | 2591 (59.1) | 3494 (62.3) |
| Male | 1389 (43.4) | 1151 (40.7) | 402 (34.0) | 961 (34.6) | 1791 (40.9) | 2112 (37.7) |
| Age of onset a | 74.4 (8.5) | 73.7 (8.4) | 74.5 (7.8) | 73.1 (8.5) | 74.5 (8.3) | 73.4 (8.5) |
| Age at consent a | 75.9 (6.9) | 74.9 (7.2) | 78.3 (6.6) | 76.1 (7.1) | 76.7 (6.8) | 75.4 (7.1) |
| Age at last visit a | 80.6 (8.2) | 80.5 (8.1) | 82.4 (8.9) | 80.8 (8.0) | 81.1 (8.0) | 80.6 (8.1) |
| Last MMSE a | 16.4 (6.1) | 15.9 (6.7) | 15.4 (6.3) | 13.7 (6.7) | 16.2 (6.2) | 14.8 (6.8) |
| Last CDR a | ||||||
| 0.0 | 2 (0.1) | 0 (0.0) | 0 (0.0) | 5 (0.2) | 2 (0.05) | 5 (0.1) |
| 0.5 | 174 (5.2) | 57 (1.9) | 70 (5.2) | 94 (3.2) | 244 (5.9) | 151 (2.8) |
| 1.0 | 1,242 (37.1) | 925 (30.8) | 266 (19.8) | 490 (16.5) | 1508 (36.8) | 1415 (26.3) |
| 2.0 | 719 (21.5) | 634 (21.1) | 368 (27.4) | 768 (25.9) | 1087 (26.5) | 1402 (26.0) |
| 3.0 | 437 (13.1) | 460 (15.3) | 280 (20.8) | 693 (23.4) | 717 (17.5) | 1153 (21.4) |
| 4.0 | 291 (8.7) | 438 (14.6) | 55 (4.1) | 310 (10.5) | 346 (8.4) | 748 (13.9) |
| 5.0 | 483 (14.4) | 487 (16.2) | 306 (22.8) | 602 (20.3) | 199 (4.9) | 508 (9.4) |
Abbreviations: AD+A, Alzheimer's disease with affective disturbance; AD‐A, Alzheimer's disease without affective disturbance; AD+P, Alzheimer's disease with psychosis; AD‐P, Alzheimer's disease without psychosis; CDR, CDR® Dementia Staging Instrument; MMSE, Mini‐Mental State Examination.
a
Data not available for some subjects/program sources. See Supplementary Material for details.