Table IV.

Comparison of [³H]-NPA binding constants in WT and tt4(2YY6) rosette microsomal membranes

Binding Constanta	WT	tt4(2YY6)
Bmaxb	0.15 ± 0.02	0.20 ± 0.04
Kdb	15.7 ± 2.2	18.5 ± 4.1

^aReported values were derived from double-reciprocal plots and represent the average and se of four experiments using six concentrations of [³H]-NPA. K_d is calculated as −1/x intercept and is reported in nanomoles; B_max is defined as 1/y intercept and is reported as picomoles per milligram. 

^bStudent's t test analysis revealed no significant difference in K_d or B_max values between WT and tt4(2YY6) microsomal membranes.