Table 1.
Preformed mediators stored within MC secretory granules
| Biogenic amines |
| Histamine |
| Serotonin |
| Dopamine |
| Polyaminesa |
| Lysosomal enzymes |
| β-Hexosaminidase |
| β-Glucuronidase |
| β-d-galactosidase |
| Arylsulfatase A |
| Cathepsin C |
| Cathepsin B |
| Cathepsin L |
| Cathepsin D |
| Cathepsin E |
| Proteoglycans |
| Serglycin (with heparin and/or CS GAG chains) |
| Proteases |
| Chymaseb |
| Tryptaseb |
| MC-CPA |
| Cathepsin G |
| Granzyme B |
| MMP-9 |
| Renin |
| Cytokines |
| TNFα |
| IL-4 |
| TGFβ |
| bFGF-2 |
| IL-15 |
| NGF |
| VEGF |
| Stem cell factor |
| Other |
| Heparanase |
| MBP |
| Peroxidase |
| LL-37/cathelicidine |