Fig. 2.

Effects of acetylation on the non-histone substrates of MYST acetyltransferases. Acetylation of a non-histone substrate by a MYST enzyme can have an impact on its stability and degradation rate. Acetylation can also regulate enzymatic or transcription factor activity. Substrate modification modulates the interaction between proteins, e.g., subunits of the same complex, or affects localization and recruitment to functional sites in the cell