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. 2010 Oct 21;68(7):1115–1129. doi: 10.1007/s00018-010-0551-z

Fig. 4.

Fig. 4

Structural organization of Cx26 monomer and hexamer. a Topological map of mutations associated with deafness and skin disease, adapted from [51]. b Intramolecular interactions that stabilize the monomer structure of Cx26. c Intermolecular interactions between two neighboring monomers in a connexon. Each interaction is shown in the enlarged insets