Table 1.

Proteins identified by LC-MS/MS in the different spots selected in Fig. 4c and amounting to at least 70% of the spot

Spot	Accession number	Protein	MS/MS scans (n)	Peptides (n)	Protein sequence coverage of peptides (%)	Molecular weight	Relative abundancea
1	P11442	Clathrin heavy chainb	254	57	37.5	191,475	99
2	Q66HF1	NADH-ubiquinone oxidoreductase 75 kDa subunit	224	28	44.7	79,362	89
3	P15999	ATP synthase subunit alpha	515	25	50.4	59,716	78
	P10719	ATP synthase subunit beta	214	25	71	56,318	21
4	P10719	ATP synthase subunit beta	564	31	72.6	56,318	71
	P15999	ATP synthase subunit alpha	387	24	46.6	59,716	28
5	P10719	ATP synthase subunit beta	294	29	71.6	56,318	72
	P32551	Cytochrome b-c1 complex subunit 2	97	17	42	48,366	27
6	P10719	ATP synthase subunit beta	99	24	68	56,318	40
	P35435	ATP synthase subunit gamma	44	9	23.4	30,171	40
7	Q68FY0	Cytochrome b-c1 complex subunit 1	87	10	28.1	52,815	46
	P10719	ATP synthase subunit beta	87	24	63.5	56,318	17
	P50554	4-Aminobutyrate aminotransferase	54	14	38.4	56,419	23
8	P3255	Cytochrome b-c1 complex subunit 2	119	19	40.5	48,366	89.5
9	P17764	Acetyl-CoA acetyltransferase	52	10	28	44,666	19
	Q8VHF5	Citrate synthase	44	10	22.1	51,833	51
10	Q05962	ATP/ADP translocase 1	49	9	23.5	32,968	32
	P00406	Cytochrome c oxidase subunit 2	27	4	24.6	25,925	40
	Q09073	ATP/ADP translocase 2	6	2	8	32,880	10
11	Q9ER34	Aconitase hydratase	283	31	41.3	85,380	88
12	P06685	Na/K-transporting ATPase subunit alpha 1b	132	26	31	112,982	31
	P06687	Na/K-transporting ATPase subunit alpha 3b	112	15	18	111,620	27
	P06686	Na/K-transporting ATPase subunit alpha 2b	101	24	23.5	112,145	15

^aCalculated from the MS signal. Corresponds to the ratio of the peak area under the reconstructed ion chromatogram (RIC) of each m/z identifying the protein to the peak area of the RIC of every identified m/z

^bPlasma and other membranes