Fig. 4.
Schematic representation of cholesterol efflux. When intracellular cholesterol is low, miR-33 and its host gene SREBF2 are up-regulated and inhibit cholesterol efflux through ABCA1 (in human and mouse cells) and ABCG1 (in mouse cells)
Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.