Figure 4.

Domain-specific functional organization within the default mode network (DMN). (a) Different areas within the medial parietal cortex respond during the recollection of familiar faces and scenes. These areas show an alternating pattern of domain preferences along the axis of the cingulate sulcus. Panel a adapted from Silson et al. (2019) (CC0 1.0). (b) Resting-state functional connectivity identifies two parallel, interdigitated networks within the DMN. Signals from within network are spontaneously correlated across different lobes and hemispheres but are not correlated across networks. Panel b adapted from Braga & Buckner (2017) (CC BY 4.0). (c) Distinct subnetworks within the DMN respond when imagining events involving familiar people and places (responses from a representative individual subject). Data for panel c from Deen & Freiwald (2021). (d) Responses to multiple tasks that involve thinking about familiar people and places, extracted from person- and place-preferring regions within the DMN (medial parietal cortex is shown as an example; similar response profiles are observed in other areas). These results demonstrate the domain specificity of functional responses within the DMN. Furthermore, they show that similar regions respond to tasks that involve thinking about familiar people, and a standard theory of mind (ToM) localizer. Data for panel d from Deen & Freiwald (2021).