Table 148.

Summary phenotype table noting the differences between human and murine cells

Antigen	Mouse		Human
	Molecules/synonyms	Expression density	Molecules/synonyms	Expression density
MHC class I	MHC class I, all H-2 molecules	+	all HLA-A, -B, -C, -G, -E alleles	+*
	H-2K	+
	H-2D	+
	H-2L	+
	beta2-microglobuline, b2m	+	beta2-microglobuline, b2m
MHC class II	I-A, I-E	−	HLA-DR	−
			HLA-DQ	−
			HLA-DP	−
NKG2D ligands	Rae-1γ	Lo	ULBP2	lo
	H60	Lo	ULBP5, 6	lo
	MULT1	Lo	ULBP4	lo
	Rae-1α	Lo	ULBP1	lo
	none	NA	MICA	lo
	none	NA	MICB	lo
	Rae-1ε	Lo	ULBP3	lo
ICAM-1	CD54	+	CD54	+
VCAM	CD106	+	CD106	+
Ep-CAM	CD326	+	CD326	+
VE-cadherin	CD144	+	CD144	+
E-cadherin	CD234	+	CD234	+
EGFR	HER1	+	HER1	+
PDGFR	CD140a (alpha chain)	+	CD140a (alpha chain)	+
	CD140b (beta chain)	+	CD140b (beta chain)	+
c-Met	HGF-receptor	+	HGF-receptor	+
Pan-cytokeratin	pan-cytokeratin	+	pan-cytokeratin	+
Cytokeratin 18	CK18	+	CK18	+
Cytokeratin 8	CK8+CK18	+	CK8	+
CD24	CD24	−**	CD24	−**
CD34	CD34	−**	CD34	−**
CD44	CD44	−**	CD44	−**
CD99	CD99		MIC2; single-chain type-1 glycoprotein	+
CD133	CD133	−**	CD133

⁺Indicates high expression,−indicates no expression, lo indicates low expression, NA indicates not applicable.

^*lost upon escape

^**potential tumor stem cell marker