Table 2.
Characteristics of dose fractionation regimens for prior RT, Re-RT and outcome
| Patient | Prior RT dose (Gy, RBE) |
Prior RT Fr |
Prior RT modality |
Re-RT dose (Gy, RBE) |
Re-RT Fr |
Total EQD2 (α/β = 10) |
Recurrence type after Re-RT |
Recurrence time after Re-RT (months) | Survival time after Re-RT (months) | Clinical outcome |
|---|---|---|---|---|---|---|---|---|---|---|
| #1 | 45.0 | 25 | Photon | 70.0 | 35 | 114.2 | 42.1 | NED | ||
| #2 | 30.0 | 20 | Photon | 67.2 | 28 | 98.2 | Distant (lung) | 3.1 | 31.4 | DOD |
| #3 | 40.0 | 20 | Photon | 75.0 | 30 | 118.1 | Distant (lung, bone) | 7.9 | 22.1 | DOD |
| #4 | 72.0 | 30 | PBT | 66.0 | 30 | 141.5 | Distant (lung, paraaortic LN) |
2.9 | 14.7 | DOD |
| #5 | 50.0 | 25 | Photon | 74.0 | 37 | 124 | Distant (liver) | 9.0 | 20.3 | DOD |
| #6 | 56.0 | 28 | Photon | 60.0 | 24 | 118.5 | Local and Distant (peritoneal dissemination) | 3.4 | 16.1 | DOD |
| #7 | 60.0 | 30 | Photon | 77.0 | 35 | 138.3 | Local | 6.5 | 26.0 | DOD |
| #8 | 74.8 | 34 | PBT | 74.8 | 34 | 152.1 | Distant (lung) | 2.2 | 59.8 | DOD |
| #9 | 50.0 | 25 | Photon | 56.0 | 28 | 106 | Local | 9.0 | 36.3 | DOD |
| #10 | 50.4 | 28 | Photon | 74.8 | 34 | 125.6 | Local | 15.5 | 41.1 | DOD |
DOD = died of disease; EQD2 = equivalent dose in 2 Gy fraction; Fr = fractionation; LN = lymph node; NED = no evidence of disease; PBT = proton beam therapy; Re-RT = reirradiation; RT = radiation therapy.