Table 2.

Blood pressure responses in WT and α1-adrenoceptor subtype KO mice

Parameter	WT	α1A-KO	α1B-KO	α1D-KO	Notes	Ref.
Conscious tail cuff SBP (mmHg)	114	104*	/	/		[128]
	99	/	99	93*	1B/1D double KO: 92*	[89]
	108.7	/	/	99.1*	1A/1B double KO: 112	[97]
	111	/	/	/		[129]
Conscious invasive MAP (mmHg)	138	121*	/	/	24 h post surgery	[128]
	119.3	/	118.5	/	3 h post surgery	[88]
	118	/	111	109*	1B/1D double KO: 103*; 24 h post surgery	[89]
	116.5	/	/	106.9*	24 h post surgery	[97]
Phe pressor		No change [128]	Decrease [88]	Small decrease [97]
			No change [89]	No change [89]	1B/1D double KO: decrease [89]
NA pressor			Small decrease [88]	Small decrease [97]
			Small decrease [89]	Decrease [89]	1B/1D double KO: decrease [89]

Results taken from [88, 89, 97, 128, 129]

SBP systolic blood pressure (recorded by tail cuff), HR heart rate, MAP mean arterial pressure (recorded by invasive cannula), phe pressor pressor response to phenylephrine relative to WT, NA pressor pressor response to noradrenaline relative to WT

*Significant difference from respective WT