Table 3.
Permeability coefficients of both HUVEC types on different coated transwell filters using low (4 kDa) and high (70 kDa) molecular weight fluorescent dextran as tracer
| Filter coating | Low molecular weight (4 kDa) | HIgh molecular weight (70 kDa) | ||||
|---|---|---|---|---|---|---|
| PE × 10−7 (cm/s) | SEM | Significance to uncoated | PE × 10−7 (cm/s) | SEM | Significance to uncoated | |
| HUVEC | ||||||
| Uncoated | 23.6 | 6.0 | – | 4.0 | 0.7 | – |
| Gelatin | 16.9 | 5.2 | No | 1.8 | 0.3 | Yes |
| Collagen I | 32.5 | 7.8 | No | 5.4 | 1.5 | Yes |
| Fibronectin | 24.2 | 7.8 | No | 4.4 | 1.0 | Yes |
| HUVEC-hTERT | ||||||
| Uncoated | 19.3 | 6.8 | – | 5.3 | 1.5 | – |
| Gelatin | 15.7 | 5.4 | No | 1.3 | 0.3 | Yes |
| Collagen I | 18.2 | 5.1 | No | 7.2 | 1.8 | Yes |
| Fibronectin | 19.9 | 5.9 | No | 5.6 | 1.4 | Yes |
PE Permeability coefficient, SEM standard error of the mean. Significance: P < 0.05