Table 1.
Characteristics of the study population
| Variables | Healthy control subjects (n = 40) | AMI patients | ||
|---|---|---|---|---|
| All (n = 80) | With HF (n = 21) | Without HF (n = 59) | ||
| Clinical and biomedical | ||||
| Age (years) | 57.1 ± 9.4 | 62.1 ± 10.8 | 66.6 ± 10.9 | 60.3 ± 11.9 |
| Men (%) | 66.1 | 78.5 | 66.7 | 83.7 |
| BMI (kg/m2) | 23.9 ± 4.2 | 28.0 ± 4.6 | 29.0 ± 4.8 | 27.7 ± 4.8 |
| CK (U/L) | – | 2,149.3 ± 2,022.3 | 3,029.7 ± 2,580.8 | 1,924.6 ± 1,819.4 |
| Peak CK-MB (ng/ml) | – | 205.2 ± 162.1 | 226.3 ± 169.4 | 193.3 ± 157.9 |
| Troponin I at peak (ng/ml) | – | 74.9 ± 61.1 | 89.2 ± 86.4 | 52.5 ± 49.8 |
| BNP (pg/ml) | – | 111.6 ± 87.3 | 124.1 ± 95.5 | 108.4 ± 85.9 |
| CRP (mg/dl) | 0.6 ± 0.4 | 3.7 ± 6.4 | 7.8 ± 12.1 | 2.6 ± 2.9 |
| Cytokines | ||||
| TNF-α (pg/ml) | 17.8 ± 7.5 | 28.3 ± 11.7 | 36.9 ± 16.4 | 25.4 ± 7.8 |
| OPG (pg/ml) | 99.7 ± 36.3 | 168.4 ± 80.1 | 195.6 ± 100 | 158.4 ± 70.6 |
| TRAIL (pg/ml) | 75.4 ± 17.9 | 50.4 ± 20.6 | 32.7 ± 18.5 | 56.7 ± 17.6 |
| OPG/TRAIL ratio | 1.6 ± 0.8 | 4.5 ± 4.2 | 8.3 ± 6.1 | 3.2 ± 2.0 |
Values given as percentage or as mean ± SD
BMI Body mass index, BNP B-type natriuretic peptide, CK creatine kinase, CK-MB creatine kinase-MB fraction, CRP C-reactive protein