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Posttranslational modifications of ERβ: the signaling cascades leading to the respective modification (green), and the effects of the modification on ERβ (blue). AF Activation function, DBD DNA binding domain, LBD ligand binding domain, Palm palmitoylation, PAT palmitoyltransferase, P phosphorylation, GlnNAc 2-amino-2-deoxyglucosylation, n.i. not investigated, ERK extracellular signal-regulated, EGF epidermal growth factor, IGF insulin-like growth factor
