Table 1.

The human PRMT family members

Name	PRMT1	PRMT2	PRMT3	PRMT4	PRMT5	PRMT6	PRMT7	PRMT8	PRMT9	PRMT10	PRMT11
Other aliases/synonyms	ANM1 HCP1 IR1B4 HRMT1L2	MGC11137 HRMT1L1	HRMT1L3	CARM1	JBP1 SKB1 IBP72 SKB1hs HRMT1L5	FLJ10559 HRMT1L6	FLJ10640 KIAA1933	HRMT1L4	FBXO11 VIT1 UBR6 FLJ12673 MGC44383	LOC90826 FLJ46629	FBX10 FBXO10 FLJ41992 MGC149840
Enzyme type	I	Unknown	I	I	II	I	II	I	II	Unknown	Unknown
Chromosomal localization	19q13.3	21q22.3	11p15.1	19p13.2	14q11.2	1p13.3	16q22.1	12p13.3	2p16.3	4q31.23	9p13.2
RefSeq transcript(s)
Variant 1	NM_001536	NM_206962	NM_005788	NM_199141	NM_006109	NM_018137	NM_019023	NM_019854	NM_025133	NM_138364	NM_012166
Variant 2	NM_198319	NM_001535			NM_001039619				NM_018693
Variant 3	NM_198318								NM_012167
Variant 4									AK022735
RefSeq protein(s)
Isoform 1	NP_001527	NP_996845	NP_005779	NP_954592	NP_006100	NP_060607	NP_061896	NP_062828	NP_079409	NP_612373	NP_036298
Isoform 2	NP_938075	NP_001526			NP_001034708				NP_061163
Isoform 3	NP_938074								NP_036299
Isoform 4									BAB14214
Length Isoform 1 (aa)	371	433	531	608	637	316	692	394	843	845	956
Length Isoform 2 (aa)	347	433			620				686
Length Isoform 3 (aa)	353								585
Length Isoform 4 (aa)									561
Cellular localization
Nucleus	+	+	−	+	−	+	+	−	+	Unknown	Unknown
Free cytoplasm	+	+	+	−	+	−	+	−	+	Unknown	Unknown
Plasma membrane	−	−	−	−	−	−	−	+	−	Unknown	Unknown

Listed are the PRMT family members, their aliases and synonyms, the enzyme types, and the chromosomal localization in the human genome. The RefSeq transcripts of the variants and the RefSeq protein isoforms are indicated as described in GenBank. The length of the major isoforms are included with the corresponding amino acids (aa). The cellular localization of the PRMTs are indicated as positive (+) or negative (−) in the nucleus, free cytoplasm, or the plasma membrane