Table 1.

Functional classification of direct KLF5 target genes

Functions	Target genes	References
Cell cycle	Cyclin D1, Cyclin B1, Cdc2, p15, p27	[30, 40, 49, 75, 79, 128]
Angiogenesis	PDGFα, VEGFα, FGF-BP	[40, 41, 55, 59, 129]
Inflammation	MCP-1, NF-κB	[56, 124]
Apoptosis	Survivin, Pim1	[45, 80]
Migration	ILK, MMP9	[82, 100]
Stemness	Nanog, Tcl1, Oct3/4, Esrrb, Fbxo15	[90, 92]
Differentiation	SMemb/NMHC-B, SM22α, PAI-1, Egr-1, PPARγ, iNOS	[19, 46, 63, 117, 118, 130]
Fatty acid metabolism	Cpt1b, Ucp2, Ucp3, FASN	[38, 47]
Others	Lactoferrin, TCR Dβ1, γ-globin, MAO-A/B, KLF4, Lama1, DAF, EGFR	[18, 22, 76, 131–137]