Fig. 3.

hINO80-deficient cells exhibit S-phase prolongation and impaired DNA synthesis. a Cell-cycle profiles were determined by subjecting indicated cells to FACS analysis after staining with PI. b Indicated cells were collected every hour after release from G1/S arrest and analyzed for cell-cycle profiles by FACS. c Indicated cells were pulse-labeled with BrdU for 15 min, stained with anti-BrdU antibodies and PI before being subjected to FACS analysis. Percentages of BrdU-positive cells are shown. All the experiments in this figure were repeated several times and the same results were obtained