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. 2009 Jul 24;66(23):3663–3673. doi: 10.1007/s00018-009-0099-y

Fig. 1.

Fig. 1

ROS levels determine cellular outcomes. Induction of ROS at lower levels leads to activation of signaling pathways responsible for regulating cellular proliferation and growth. Conversely, high levels of ROS generation can lead to DNA damage, resulting in genomic instability