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. 2009 Nov 7;67(5):715–726. doi: 10.1007/s00018-009-0186-0

Table 2.

Examples of intracellular delivery of different cargoes by CPPs

CPP Cargo References
Large size cargoes
Proteins
 Tat Heterologous proteins [16]
 Tat Tumor associated proteins and peptides [81]
Nucleic acids
 Tat Gene markers encapsulated in λ phage [82]
 Various CPP Potential for CPP to deliver DNA [83]
Imaging agents
CPP for in vivo molecular imaging applications [84]
 Tat Paramagnetic labels [85]
 Tat Technetium and rhenium [86]
Nanocarriers
 Tat Pharmaceutical nanocarriers [87]
Solid lipid nanoparticles [88]
Gold nanoparticles [89]
Polymeric micelles [90]
Liposomes
 Tat, penetratin Liposomes [87, 91]
 Tat Liposomes [92]
Small size cargoes
Oligo arg Taxol [93]
Oligo arg Cyclosporine A [94]
Oligoguanidinium Various small molecules [22]
Oligonucleotides
 Arg rich peptides PMO, PNA

[42]

[95]

 Various CPP PMO, PNA [96]
Peptides
 Tat, transportan, MAP, penetratin Pentapeptide [97]
 Tat Peptidic inhibitor of Leishmania GP 63 [98]
 Tat Von Hippel Linau tumor suppressor peptide [99]