Table 1.
Overview of Demographic and Clinical Characteristics by INR Testing Group
| Overall INR testing | PST | POC/Lab | p-value | 2(df) | |
|---|---|---|---|---|---|
| (N= 37,837) | (N=1592) | (N=36,245) | |||
| Demographic characteristics | |||||
| Age at diagnosis, years | < .001 | 92.583 (1) | |||
| Mean (SD) | 60 (15) | 64 (16) | 60 (15) | ||
| Median (Q1, Q3) | 60 (51, 70) | 64 (54, 76) | 60 (51, 70) | ||
| Age at treatment index, years | <.001 | 92.776 (1) | |||
| Mean (SD) | 60 (15) | 64 (16) | 60 (15) | ||
| Median (Q1, Q3) | 60 (51, 71) | 64 (54, 76) | 60 (51, 70) | ||
| Sex | <.001 | 9.0894 (1) | |||
| Female | 16,874 (45%) | 769 (48%) | 16,105 (44%) | ||
| Male | 20,963 (55%) | 823 (52%) | 20,140 (56%) | ||
| Region | |||||
| Northeast | 6786 (18%) | 352 (22%) | 6434 (18%) | <.001 | 64.313 (4) |
| North Central | 12,115 (32%) | 469 (29%) | 11,646 (32%) | ||
| South | 12,329 (33%) | 588 (37%) | 11,741 (32%) | ||
| West | 6279 (17%) | 170 (11%) | 6109 (17%) | ||
| Missing | 328 (0.9%) | 13 (0.8%) | 315 (0.9%) | ||
| Region location | 0.200 | 0.500 (1) | |||
| Rural | 5904 (16%) | 259 (16%) | 5645 (16%) | ||
| Urban | 31,933 (84%) | 1333 (84%) | 30,600 (84%) | ||
| Clinical characteristics | |||||
| Index diagnosis | <.001 | 305.620 (4) | |||
| Atrial fibrillation | 12,160 (32%) | 639 (40%) | 11,521 (32%) | ||
| Deep vein thrombosis | 13,172 (35%) | 420 (26%) | 12,752 (35%) | ||
| Mechanical heart valve | 2657 (7.0%) | 255 (16%) | 2402 (6.6%) | ||
| Pulmonary embolism | 6575 (17%) | 181 (11%) | 6394 (18%) | ||
| More than 1 | 3273 (8.7%) | 97 (6.1%) | 3176 (8.8%) | ||
| Year of diagnosis | <.001 | 39.586 (6) | |||
| 2013 | 7309 (19%) | 273 (17%) | 7036 (19%) | ||
| 2014 | 11,900 (31%) | 451 (28%) | 11,449 (32%) | ||
| 2015 | 7678 (20%) | 311 (20%) | 7367 (20%) | ||
| 2016 | 4894 (13%) | 221 (14%) | 4673 (13%) | ||
| 2017 | 2968 (7.8%) | 163 (10%) | 2805 (7.7%) | ||
| 2018 | 1890 (5.0%) | 113 (7.1%) | 1777 (4.9%) | ||
| 2019 | 1198 (3.2%) | 60 (3.8%) | 1138 (3.1%) | ||
| Baseline hypertension | 21,055 (56%) | 966 (61%) | 20,089 (55%) | <.001 | 16.837 (1) |
| Baseline heart failure | 6409 (17%) | 385 (24%) | 6024 (17%) | <.001 | 61.466 (1) |
| Baseline valvular dis | 8191 (22%) | 632 (40%) | 7559 (21%) | <.001 | 318.130 (1) |
| Baseline diabetes | 9131 (24%) | 419 (26%) | 8712 (24%) | .110 | 4.216 (1) |
| Baseline chronic pulmonary disease | 6779 (18%) | 326 (20%) | 6453 (18%) | <.001 | 7.232 (1) |
| Baseline renal disease | 3616 (9.6%) | 180 (11%) | 3436 (9.5%) | <.001 | 5.677 (1) |
| Baseline periph vasc dis | 4927 (13%) | 312 (20%) | 4615 (13%) | <.001 | 62.86 (1) |
| Baseline cancer | 4099 (11%) | 138 (8.7%) | 3961 (11%) | <.001 | 7.832 (1) |
| Baseline obesity | 6321 (17%) | 214 (13%) | 6107 (17%) | <.001 | 12.478 (1) |
| Charlson Comorbidity Index | <.001 | 42.208 (1) | |||
| Mean (SD) | 1.83 (2.23) | 1.98 (2.10) | 1.77 (2.22) | ||
| Median (Q1, Q3) | 1.00 (0.00, 3.00) | 1.00 (0.00, 3.00) | 1.00 (0.00, 3.00) | ||
| Payer channel | <.001 | 213.27 (1) | |||
| Commercial | 25,267 (67%) | 794 (50%) | 24,473 (68%) | ||
| Medicare | 12,570 (33%) | 798 (50%) | 11,772 (32%) | ||