Fig. 1. Positive Correlation between Change Ratio of IA and RSFC from Left AIC to Left DLPFC and Right SMG.
Significant positive correlations were observed between the change ratio of IA and increased RSFC from the left AIC to (A) the left DLPFC (-40 46 32) (Pearson’s r = 0.84, p < 0.001), and (B) the right SMG (-12 16 42) (Pearson’s r = 0.79, p < 0.001), illustrated by the blue and the red scatter plots on the right side, respectively. Vertical axes represent increased RSFC at peak voxel in each cluster, and horizontal axes indicate a change ratio of IA (i.e., Post IA/Pre IA). The statistical threshold was set at p < 0.001 and corrected to p < 0.05 for multiple comparisons using cluster size. IA interoceptive accuracy, RSFC resting state functional connectivity, AIC anterior insula cortex, DLPFC dorsolateral prefrontal cortex, SMG supramarginal gyrus, CCN cognitive control network.