Table 2.
Summary statistics of the AD patient comorbidities
| No drug treatment | Memantine | Donepezil | Donepezil/Memantine | Total | |
|---|---|---|---|---|---|
| Comorbiditiesa | N (%)b | N (%)b | N (%)b | N (%)b | N (%)b |
| Cerebral infarction (I60–I69) | |||||
| Absence | 5276 (85.72) | 1228 (84.92) | 3335 (85.25) | 1064 (86.43) | 10,903 (85.55) |
| Presence | 879 (14.28) | 218 (15.08) | 577 (14.75) | 167 (13.57) | 1841 (14.45) |
| Diabetes (E10–E13) | |||||
| Absence | 5453 (88.59) | 1286 (88.93) | 3432 (87.73) | 1096 (89.03) | 11,267 (88.41) |
| Presence | 702 (11.41) | 160 (11.07) | 480 (12.27) | 135 (10.97) | 1477 (11.59) |
| Overweight and obesity (E66) | |||||
| Absence | 6064 (98.52) | 1419 (98.13) | 3839 (98.13) | 1209 (98.21) | 12,531 (98.33) |
| Presence | 91 (1.48) | 27 (1.87) | 73 (1.87) | 22 (1.79) | 213 (1.67) |
| Hypertensive diseases (I10) | |||||
| Absence | 5425 (88.14) | 1264 (87.41) | 3372 (86.2) | 1061 (86.19) | 11,122 (87.27) |
| Presence | 730 (11.86) | 182 (12.59) | 540 (13.8) | 170 (13.81) | 1622 (12.73) |
| Other forms of heart disease (I3–I5) | |||||
| Absence | 4734 (76.91) | 1085 (75.03) | 2939 (75.13) | 964 (78.31) | 9722 (76.29) |
| Presence | 1421 (23.09) | 361 (24.97) | 973 (24.87) | 267 (21.69) | 3022 (23.71) |
| Acute kidney injury and chronic kidney disease (N17–N19) | |||||
| Absence | 4488 (72.92) | 1062 (73.44) | 2790 (71.32) | 897 (72.87) | 9237 (72.48) |
| Presence | 1667 (27.08) | 384 (26.56) | 1122 (28.68) | 334 (27.13) | 3507 (27.52) |
| Total | 6155 (100) | 1446 (100) | 3912 (100) | 1231 (100) | 12,744 (100) |
aDesignations in parenthesis are ICD-10 codes.
bN (%) represent the frequency count of each comorbidity and the corresponding percent of each comorbidity within treatment and in the total sample.