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. 2024 May 10;15:1387950. doi: 10.3389/fimmu.2024.1387950

Table 7.

Summarized results of the T-cell search.

Type of study (N, # groups) Basal diet Zn Zn supplement & formulation
[Zn dose]
Route Duration of supplementation Animals Outcomes* Findings Reference
RCT (N=72, 3) 0 mg/kg A. 7 g/d organic trace mineral mix
[951 mg/d Zn]
PO 42 days 284 ± 25 kg angus crossbred steers Activation surface marker expression without stimulation (CD2, CD16, CD25, CD44, CD45RO) CD25 MFI
 C > A &
 B, day 42
% CD45RO cells
 B > A &
 C, day 0
(17)
B. 7 g/d organic trace mineral mix & 1000 mg/d Zn AA for 14 days then only the organic trace mineral mix
[1900, 929 mg/d Zn]
14 days, 28 days
C. Inorganic trace mineral mix formulated to match group A.
[1095 mg/d Zn]
42 days

RCT, randomized controlled trial; Zn, zinc; mg, milligram; kg, kilogram; g, gram; d, day; AA, amino acid complex; PO, per oral; CD, cluster of differentiation. *Only stimulations and outcomes relevant to the assessment of T-cells are listed.