Table 1.
The recent advances of ncRNAs in HCC.
| Non-coding RNA | Remark | Reference |
|---|---|---|
| Circ_0004913 | Inhibition of proliferation, metastasis, and glycolysis through absorbing miR-184 | (338) |
| Circ_KIAA1429 | Increasing tumorigenesis Upregulation of HMGA2 |
(339) |
| Circular RNA hsa_circ_0005218 | Increasing early occurrence of hepatocellular carcinoma Binding to miR-31-5p to increase CDK1 levels |
(340) |
| Hsa_circ_0010882 | Increasing M2 polarization of macrophages | (341) |
| Circular RNA hsa_circ_0098181 | Interaction with eEF2 to stimulate Hippo signaling for impairing invasion and migration of tumor cells | (342) |
| Circular RNA circ_0003028 | Inhibition of miR-498 to increase ornithine decarboxylase 1 levels | (343) |
| Circ_0073228 | Increase in the growth of tumor cells and suppression of apoptosis | (344) |
| Hsa_circ_001726 | Sponging miR-671-5p to increase PRMT9 levels in enhancing invasion and metastasis | (345) |
| Hsa_circ_0000092 | Binding to miR-338-3p to increase HN1 levels in tumorigenesis | (346) |
| Circ_MAPK9 | miR-642b-3p inhibition to enhance STAT3 and LDHA levels | (347) |
| Circ_HMGCS1 | Sponging miR-338-5p to increase IL-7 levels in cisplatin resistance | (348) |
| Circ-EIF3I | Inhibition of miR-361-3p to increase DUSP2 levels in enhancing tumorigenesis | (349) |
| CircZCCHC2 (hsa_circ_0000854) | Stimulation of the Rho/ROCk2 axis and the regulation of miR-936/BTBD7 to elevate tumorigenesis | (350) |
| LncRNA MIR4435-2HG | Increase in stemness through regulation of rRNA 2’-O methylation | (351) |
| LncRNA FAM99B | FAM99B can be derived from exosomes of mesenchymal stem cells to suppress tumorigenesis | (352) |
| LncRNA FAM13A-AS1 | LncRNA FAM13A-AS1 is transcriptionally modulated by PHOX2B to increase PPARγ stability to control drug resistance | (353) |
| LncRNA SNHG16 | The exosomal SNHG6 can enhance the metastasis of hepatocellular carcinoma through upregulating MMP9 | (354) |
| LncRNA SLC2A1-DT | Positive interaction with c-Myc to increase carcinogenesis | (355) |
| LncRNA HEIH | Binding to miR-193a-5p to upregulate CDK8 to enhance growth and invasion | (356) |
| LncRNA RP11-620J15.3 | Increase in glycolysis | (357) |
| LncRNA SNHG1 | SNHG1 sponges miR-7-5p to increase IGF2BP2 levels | (358) |
| miR-612 | miR-612 promotes RSL3-mediated ferroptosis | (359) |
| miR-375 | miR-375 suppresses autophagy to disrupt sorafenib resistance | (360) |
| LINC00607 | LINC00607 is induced by MYC and can promote tumorigenesis through miR-584-3p sponging and upregulating ROCK1 | (361) |
| CircCPSF6 | Sponging miR-145-5p to increase MAP4K4 levels | (362) |
| miR-26a | Tumor exosomes can deliver miR-26a to reduce lymphoid enhancer factor 1 levels in impairing tumorigenesis | (363) |
| CircTMEM181 | Upregulation of ARHGAP29 through inhibition of miR-519a-5p to impair metastasis | (364) |
| Hsa_circ_0129047 | Sponging miR-492 to increase LYVE1 levels in impairing tumorigenesis | (365) |
| Circ-SNX27 | Accelerating tumorigenesis through sponging the miR-375/RPN1 axis | (366) |
| Hsa_circ_0000098 | Sponging miR-136-5p to increase MMP2 levels | (367) |