Table 3.
Sensitivity analysis of LBP causally linked to hormonal and reproductive factors.
| Exposure | Outcome | Pleiotropy | Heterogeneity | ||
|---|---|---|---|---|---|
| Horizontal pleiotropy (Egger intercept) | Horizontal pleiotropy (p-value) | Heterogeneity (Q) | Heterogeneity (p-value) | ||
| LBP | ANM | -0.004 | 0.217 | 28.511 | 0.074 |
| AAM | -4.38E-04 | 0.855 | 59.342 | 4.92E-06 | |
| LMC | -0.003 | 0.582 | 25.735 | 0.138 | |
| AFB | -0.002 | 0.454 | 41.314 | 0.002 | |
| ALB | -0.001 | 0.622 | 25.842 | 0.135 | |
| AFS | -0.001 | 0.534 | 40.063 | 0.001 | |
ANM, age at menopause; AAM, age at menarche; LMC, length of menstrual cycle; AFB, age at first birth; ALB, Age at last live birth; AFS, Age first had sexual intercourse; BMI, Body mass index; LBP, low back pain.