TABLE 2.

Aza-Henry reaction of N-Boc trifluoromethyl ketimines catalyzed by the ion-pair catalyst ^a .

^a Unless otherwise noted, the reaction was performed with 1 (0.1 mmol), 2 (0.20 mmol), catalyst 4f (1 mol%), and base (0.1 equiv.) in solvent (1.0 mL) for 3 days.

^b After recrystallization.

^c Catalyst 4e (5 mol%) and K₂CO₃ (2.0 equiv.) were used.