Table 1.
Baseline characteristics.
| Variables | Total (n=66) |
|---|---|
| Age, years, median (range) | 57.5 (29.0-79.0) |
| Sex (male) | 37 (56.1) |
| BMI | |
| <18.5 | 1 (1.5) |
| 18.5-24 | 51 (77.3) |
| >24 | 14 (21.2) |
| History of HBV infection | 21 (31.8) |
| KPS | |
| 50 | 1 (1.5) |
| 60 | 3 (4.5) |
| 70 | 12 (18.2) |
| 80 | 49 (74.2) |
| 90 | 1 (1.5) |
| CEA, ng/mL (<5) | 49 (73.1) |
| CA19-9, U/mL (<34) | 27 (40.9) |
| Lymphocyte, 10^9/L, median (quartile) | 1.30 (0.98-1.78) |
| Neutrophil, 10^9/L, median (quartile) | 3.59 (2.54-5.03) |
| Platelet, 10^9/L, median (quartile) | 190.50 (150.00-263.75) |
| ALT, U/L, (<33) | 44 (66.7) |
| AST, U/L, (<32) | 40 (60.6) |
| ALB, g/L, (<35) | 7 (10.6) |
| LDH, U/L, (<214) | 44 (66.7) |
| TBil,μmol/L, (<21) | 58 (87.9) |
| FIB-4, median (quartile) | 1.72 (1.26-2.26) |
| SII, median (quartile) | 472.34 (329.15-885.45) |
| NLR, median (quartile) | 2.60 (1.80-4.11) |
| PLR, median (quartile) | 137.08 (105.18-190.33) |
| PNI, median (quartile) | 46.50 (43.45-51.13) |
| Child-Pugh stage | |
| A | 62 (93.9) |
| B | 4 (6.1) |
| Histological type | |
| Adenocarcinoma | 63 (95.5) |
| Other types | 3 (4.5) |
| Differentiation | |
| Well | 1 (1.5) |
| Medium | 48 (72.7) |
| Poor | 17 (25.8) |
| Ki67, median (quartile) | 40 (15-69) |
| Tumor number | |
| Single | 27 (40.9) |
| Multiple | 39 (59.1) |
| Tumor site | |
| Intrahepatic | 57 (86.4) |
| Perihilar | 7 (10.6) |
| Distal | 2 (3.0) |
| Largest tumor diameter, cm, median (quartile) | 4.8 (2.8-7.1) |
| Macrovascular invasion | 10 (15.2) |
| Local lymph node metastasis | 33 (50.0) |
| Liver metastasis | 36 (54.5) |
| Extrahepatic metastasis | |
| Omentum majus | 2 (3.0) |
| Lung | 3 (4.5) |
| Brain | 1 (1.5) |
| Stomach | 1 (1.5) |
| Supraclavicular lymph nodes | 2 (3.0) |
| Bone | 2 (3.0) |
| Pancreas | 3 (4.5) |
Values are presented as median (quartile) or n (%).
BMI, body mass index; HBV, hepatitis B virus; KPS, Karnofsky performance status score; CEA, carcinoembryonic antigen; CA19-9, carbohydrate antigen 19-9; ALT, alanine transaminase; AST, aspertate aminotransferase; ALB, albumin; LDH, lactate dehydrogenase; Tbil, total bilirubin; FIB-4, the fibrosis-4 index; SII, systemic immune-inflammation index; NLR, neutrophil-to-lymphocyte ratio; PLR, platelet-to-lymphocyte ratio; PNI, prognostic nutritional index.