Table 2.

Associations of insulin doses and numbers of days with data uploads over a 14-day period with glycemic outcomes in the basal-bolus cohort

Response	Missed basal dose	Missed bolus dose	Daily bolus injection	Days with data uploads
TIR 3.9–10.0 mmol/L, %
Slope (95% CI)	−2.76 (−3.73, −1.79)	−1.73 (−1.84, −1.62)	1.55 (1.21, 1.89)	0.47 (0.35, 0.60)
P	<0.0001	<0.0001	<0.0001	<0.0001
TAR >10.0 mmol/L, %
Slope (95% CI)	2.90 (1.87, 3.93)	1.80 (1.68, 1.91)	−1.71 (−2.07, −1.34)	−0.41 (−0.54, −0.27)
P	<0.0001	<0.0001	<0.0001	<0.0001
TAR >13.9 mmol/L, %
Slope (95% CI)	3.25 (2.43, 4.07)	1.40 (1.31, 1.49)	−1.55 (−1.84, −1.26)	−0.24 (−0.35, −0.13)
P	<0.0001	<0.0001	<0.0001	<0.0001
TBR <3.9 mmol/L, %
Slope (95% CI)	−0.13 (−0.34, 0.08)	−0.07 (−0.09, −0.04)	0.16 (0.09, 0.23)	−0.06 (−0.09, −0.04)
P	0.2141	<0.0001	<0.0001	<0.0001
TBR <3.0 mmol/L, %
Slope (95% CI)	0.01 (−0.05, 0.06)	0.00 (−0.00, 0.01)	0.01 (−0.00, 0.03)	−0.02 (−0.02, −0.01)
P	0.8276	0.8059	0.1420	<0.0001
Mean glucose concentration, mmol/L
Slope (95% CI)	0.46 (0.34, 0.58)	0.20 (0.19, 0.21)	−0.22 (−0.26, −0.18)	−0.03 (−0.05, −0.02)
P	<0.0001	<0.0001	<0.0001	<0.0001
GMI score, %
Slope (95% CI)	0.20 (0.15, 0.25)	0.09 (0.08, 0.09)	−0.10 (−0.11, −0.08)	−0.01 (−0.02, −0.01)
P	<0.0001	<0.0001	<0.0001	<0.0001
%CV
Slope (95% CI)	−0.26 (−0.59, 0.07)	0.42 (0.38, 0.46)	0.28 (0.16, 0.39)	−0.22 (−0.26, −0.18)
P	0.1176	<0.0001	<0.0001	<0.0001

Between-individual effects (N = 3,945). The presented data include estimated regression coefficients (slope) with 95% CI. Headers show individual-level parameters, calculated as averages over the 14-day blocks for each individual. The regression coefficient shows that, for example, in comparison of two individuals with equal characteristics except one has on average one more missed basal insulin dose per 14 days, this individual would have a mean change in TIR of −2.76%.