Table 1. Characteristics of Matched Deceased Donors.
| Donor characteristics | Matched donorsa | Standardized mean difference | |
|---|---|---|---|
| Underwent dialysis (n = 514) | Did not undergo dialysis (n = 514) | ||
| Age, mean (SD), y | 33 (10.8) | 33.1 (10.9) | −0.014 |
| Sex | |||
| Male | 313 (60.9) | 314 (61.1) | −0.004 |
| Female | 201 (39.1) | 200 (38.9) | 0.004 |
| Raceb | |||
| Blackc | 76 (14.8) | 76 (14.8) | 0 |
| Otherd | 438 (85.2) | 438 (85.2) | 0 |
| Body mass index, mean (SD)e | 29.5 (7.1) | 29.5 (7.2) | 0.0046 |
| Estimated glomerular filtration rate at hospital admission, mean (SD), mL/min/1.73 m2 | 66.8 (30.6) | 68.2 (30.1) | −0.048 |
| Serum creatinine, median (IQR), mg/dL | |||
| Level at hospital admission | 1.4 (1 to 1.9) | 1.4 (1 to 1.8) | 0.077 |
| Peak level | 4.2 (2.1 to 6.2) | 1.8 (1.3 to 2.6) | 0.96 |
| Terminal level | 2.3 (1.2 to 4) | 1.1 (0.8 to 1.8) | 0.67 |
| Reason for dialysis | |||
| Acute kidney injury | 392 (76.3) | ||
| Intoxicationf | 71 (13.8) | ||
| Other reasong | 51 (9.9) | ||
| Dialysis modality, No./total (%) | |||
| Continuous kidney replacement therapy | 289/505 (57.2) | ||
| Hemodialysis | 201/505 (39.8) | ||
| Both | 15/505 (3.0) | ||
| Duration of dialysis, No./total (%) | |||
| ≤3 d | 374/495 (75.6) | ||
| 4-7 d | 100/495 (20.2) | ||
| >7 d | 21/495 (4.2) | ||
| No. of vasopressors and inotropes used, median (IQR) | 0 (0 to 1) | 0 (0 to 1) | 0.17 |
| Hypertension | 98 (19.1) | 98 (19.1) | 0 |
| Diabetes | 36 (7) | 36 (7) | 0 |
| Donation after cardiac death | 35 (6.8) | 35 (6.8) | 0 |
| Stroke as cause of death | 37 (7.2) | 37 (7.2) | 0 |
| Hepatitis C status | 11 (2.1) | 11 (2.1) | 0 |
| No. of kidneys transplanted | |||
| 1 | 74 (14.4) | 38 (7.4) | 0.23 |
| 2 | 440 (85.6) | 476 (92.6) | −0.23 |
| Transplant year range | |||
| 2010-2014 | 144 (28) | 143 (27.8) | −0.0043 |
| 2015-2016 | 147 (28.6) | 148 (28.8) | 0.0043 |
| 2017-2018 | 223 (43.4) | 223 (43.4) | 0 |
SI conversion factor: To convert creatinine to μmol/L, multiply by 88.4.
Data are expressed as No. (%) unless otherwise indicated. The following variables were used for matching deceased donors by dialysis status: age (by 5-year increments), sex, and Black race, body mass index categories (≤18.5, 18.5-<25, 25-<30, 30-40, and >40), hypertension, diabetes, donation after cardiac death status, stroke as the cause of death, estimated glomerular filtration rate at hospital admission (range, 0-120 mL/min/1.73 m2 by increments of 15), hepatitis C antibody positivity, and year of transplant (2010-2014, 2015-2016, or 2017-2018).
Primarily reported by the donor’s family or collected by clinical staff from the organ procurement organizations and recorded in the electronic health record.
Specifically reported by the Organ Procurement and Transplantation Network because it is associated with recipient graft outcomes.15
Includes American Indian, Asian, Pacific Islander, White, and multiple races.
Calculated as weight in kilograms divided by height in meters squared.
For poisoning from ethylene glycol, methanol, lithium, or another toxic substance or medication.
Severe hyperkalemia, acidosis, hypervolemia, hyperammonemia, and other electrolyte abnormalities without laboratory evidence of stage 2 or 3 acute kidney injury.