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. 2024 May 14;14(10):1462. doi: 10.3390/ani14101462

Table 2.

Frequency of side effects of gabapentin based on the qualitatively reported “lowest dose” administered (range 3–25 mg/kg), further divided into two quantitative mg/kg ranges in 50 dogs with behavior disorders.

Side Effect 1 No. Dogs at Each Quantitative Dosing Category (%) with Owner Reported Side Effect p-Value 2
<15 mg/kg (n = 39) 15–30 mg/kg (n = 11)
Sedation 4 (10.3%) 1 (10.0%) 1.0
Increased activity 3 (7.7%) 1 (10.0%) 1.0
Agitation 5 (12.8%) 1 (10.0%) 1.0
Increased appetite 1 (2.6%) 0 1.0
Urinary incontinence 0 1 (10.0%) 0.2
New aggression 2 (5.1%) 1 (10.0%) 0.5
One or more of the above 9 (23.1%) 4 (40.0%) 0.4

1 No side effects were reported for ataxia, vomiting, diarrhea, constipation, or increased aggression, which are therefore omitted from the table. 2 Fisher’s Exact Test.