Table 3.

Frequency of side effects of gabapentin based on the qualitatively reported “highest dose” administered (range 13.0–65 mg/kg), further divided into four quantitative mg/kg ranges in 43 dogs with behavior disorders.

Side Effect 1	No. Dogs at Each Quantitative Dosing Category (%) with Owner Reported Side Effect				p-Value 2
	<15 mg/kg (n = 3)	15–30 mg/kg (n = 9)	30.1–49.9 mg/kg (n = 23)	≥50 mg/kg (n = 8)
Sedation	1 (33.3%)	2 (22.2%)	13 (56.5%)	5 (62.5%)	0.3
Ataxia	0	3 (33.3%)	4 (17.4%)	2 (25.0%)	0.6
Increased activity	1 (33.3%)	1 (11.1%)	2 (8.7%)	0	0.4
Agitation	1 (33.3%)	3 (33.3%)	3 (13.0%)	1 (12.5%)	0.4
Increased appetite	0	1 (11.1%)	1 (4.3%)	1 (12.5%)	0.5
Diarrhea	0	0	1 (4.3%)	1 (12.5%)	0.5
Constipation	0	0	1 (4.3%)	0	1.0
Urinary incontinence	0	0	2 (8.7%)	0	1.0
Increased aggression	0	0	1 (4.3%)	0	1.0
One or more of the above	2 (66.7%)	5 (55.6%)	16 (69.6%)	6 (75.0%)	0.9

¹ No side effects were reported for vomiting or new aggression, therefore are omitted from the table. ² Fisher’s Exact Test.