Table 1.
Protective effect of apigenin on peroxynitrite-induced hypochromic alterations in aromatic amino acids of fibrinogen.
| SN. | Comparative Assessment of Hypochromicity | Alteration at λmax (Hypo or Hyper-Chromicity) |
% Protection on Hypochromicity by AP |
|---|---|---|---|
| 1. | Native Fibrinogen v/s ONOO−-Fibrinogen | 35.7% hypochromicity | - |
| 2. | AP50-ONOO−-Fibrinogen v/s Native Fibrinogen | 23.9% hypochromicity | 32.8 |
| 3. | AP50-ONOO−-Fibrinogen v/s ONOO−-Fibrinogen | 6.9% hyperchromicity | - |
| 4. | AP75-ONOO−-Fibrinogen v/s Native Fibrinogen | 20.5% hypochromicity | 42.6 |
| 5. | AP75-ONOO−-Fibrinogen v/s ONOOv-Fibrinogen | 8.9% hyperchromicity | - |
| 6. | AP100-ONOO−-Fibrinogen v/s Native Fibrinogen | 6.8% hypochromicity | 80.9 |
| 7. | AP100-ONOO−-Fibrinogen v/s ONOOv-Fibrinogen | 31.0% hyperchromicity | - |
Abbreviation: ONOO−, peroxynitrite; AP50, Apigenin at 50 µM; AP75, Apigenin at 75 µM; AP100, Apigenin at 100 µM; AP, Apigenin.