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. 2024 May 15;14(5):582. doi: 10.3390/biom14050582

Figure 4.

Figure 4

Plasma concentrations of oral Posiphen and metabolites presented as Cmax mean values with standard deviation (SD) in mice (n = 7)—(a) CSF; (b) brain—and in humans (n = 4)—(c) CSF. The SD and %CV values for each time point in mice are described in Supplementary Materials S2. Due to the low sample size for humans, the study was underpowered to perform SD calculations.