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Target genes for the oncomirs in pancreatic tumors.
| Oncomirs (Upregulated) |
miRNA Targets | miRNA Enhances |
References |
|---|---|---|---|
| miR-21 | CDK2AP1, Pdcd, BCL2, PTEN, and almost 30 genes | proliferation, invasion, chemoresistance, tumor survival | [14,15,63,64] |
| miR-155 | TP53INP1, FOXO3a, and SOCS1 | proliferation, transformation, migration, invasion | [38,59,65] |
| miR-196a | NFKBIA | proliferation, migration, invasion | [66] |
| miR-210 | Ephrin-A3, MNT | proliferation, angiogenesis, tumor growth, survival | [26,67] |
