Figure 3.

(A) Amino acid sequences of the vaccine construct. The adjuvant is colored red, MHC−I epitopes are colored blue, and MHC−II epitopes are colored brown, B-cell epitopes are colored purple, and linkers are colored green. (B) Three−dimensional (3D) structure of the vaccine construct. (C) In the Ramachandran plot of the refined 3D model generated by the PROCHECK, the red-colored regions are the most favored, the dark yellow and light yellow regions are the additional allowed and generously allowed regions, and the white regions are the disallowed regions. (D,E) The Z-score plot of the refined 3D model generated by ProSA-web. (F) The region in the structure are rejected at the 99% level are shown in red color, also the regions of the structure rejected at 95% confidence level are shown in yellow color which is generated by ERRAT.