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. 2024 May 17;11(5):505. doi: 10.3390/bioengineering11050505

Table 4.

Predicted MHC class II epitopes. The table shows the asterisk (*) in HLA-DRB signifies a specific allele variant within the HLA-DRB gene, commonly used in HLA nomenclature to denote subtype. Furthermore, the epitopes were checked for antigenicity, allergenicity, and toxicity for the design of a multi-epitope vaccine construct.

MHC-II Peptide Start HLA Alleles Antigenicity Score Allergenicity Toxicity
ALLYAYYKTDSISEK 39 HLA-DRB1 * 04:05 0.4707 (Antigenic) Non-Allergic Non-Toxic
IALSHTYISEKTQEI 21 HLA-DRB3 * 01:01 0.4331 (Antigenic) Non-Allergic Non-Toxic
KTDSISEKIRAMYEM 46 HLA-DRB1 * 13:02 0.6838 (Antigenic) Non-Allergic Non-Toxic
LLYAYYKTDSISEKI 40 HLA-DRB1 * 04:05 0.5207 (Antigenic) Non-Allergic Non-Toxic
YKTDSISEKIRAMYE 45 HLA-DRB1 * 13:02 0.4995 (Antigenic) Non-Allergic Non-Toxic