Figure 5.

Predictive value of tissue 4-HNE alone (top panel) or in combination with serum 4-HNE (bottom panel) for PHLF after liver resection (left). Event rates of PHLF (middle) and CR-PHLF (right) according to low- (vs. intermediate) vs. high-risk cut-offs (Chi-Square and Fisher’s exact test). 4-HNE = 4-hydroxynonenal; AUC = area under the curve; CI = confidence interval; CR-PHLF = clinically relevant post-hepatectomy liver failure (ISGLS Grade B or C); PHLF = post-hepatectomy liver failure; POD = postoperative day.