Table 1.

The function of USP36 in varieties of cancers.

References	Functions	Substrates	Cancer Type
[31]	Facilitating ESCC progression via the Hippo/YAP axis	Hippo/YAP	Esophageal carcinoma
[77]	Deubiquitinating Snail2 and thus promoting glioblastoma invasion and tumorigenesis	Snail2	Glioblastoma invasion
[73]	Synergizing with TP53 and promoting HCC progression	TP53	Hepatocellular carcinoma
[74]	Stabilizing CEP63 by reducing its K48 ubiquitination and promoting colorectal cancer progression	CEP63	Colorectal cancer
[75]	Deubiquitinating PKM2 to suppress the malignant phenotypes through the Warburg effect	PKM2	Breast cancer
[76]	USP36 helps mediate the stabilization of EZH2	MELK	T cell lymphoma