TABLE 1.
Summary of quorum sensing systems described so far in enteric bacteria
| Bacterial species | QS system | Autoinducer(s) | Regulated phenotype(s) |
|---|---|---|---|
| EHEC and EPEC | Qse/LuxS | AI-3 | TTS, flagella, and motility |
| Lsr/LuxS | AI-2 (R-THMF)a | AI-2 uptake by Lsr | |
| SdiA | AHLs (not self-produced) | ? | |
| Salmonella sp. | Qse/LuxS | AI-3 | ? |
| Lsr/LuxS | AI-2 (R-THMF) | AI-2 uptake by Lsr; biofilm formation? | |
| SdiA | AHLs (not self-produced) | Resistance to human complement (Rck) | |
| Vibrio cholerae | System 1 (CqsA/CqsS) | CAI-1 | TCP, CT, HA protease, biofilm |
| System 2 (LuxS) | AI-2 (furanosyl-borate diester?) | TCP, CT, HA protease, biofilm | |
| System 3 | ? | ? | |
| EAEC | Qse/LuxS | AI-3 | ? |
| Lsr/LuxS | AI-2 (R-THMF) | ? | |
| SdiA | AHLs (not self-produced) | ? | |
| Other? | ? | AggR-regulated virulence genes | |
| Enterococcus faecalis | Cyls | CyILs | Cytolysin production |
| FsR | Peptide | Gelatinase, serine protease | |
| LuxS | AI-2 | ? | |
| Yersinia sp. | Qse/LuxS | AI-3 | ? |
| Lsr/LuxS | AI-2 | ? | |
| YenR/I | AHLs | ? | |
| YpsR/I | AHLs | Flagella and motility | |
| YtbR/I | AHLs | Flagella and motility | |
| Shigella flexneri | Qse/LuxS | AI-3 | Expression of VirB? |
| Lsr/LuxS | AI-2 | Expression of VirB? | |
| Campylobacter jejuni | LuxS | AI-2 | Motility |
| Vibrio vulnificus | LuxS | AI-2 (furanosyl-borate diester?) | Protease, hemolysin |
| SmrC | ? | Protease, hemolysin, virulence | |
| Vibrio parahaemolyticus | LuxM, LuxR (OpaR) | AI-1 (AHL?) | TTS |
| LuxP, LuxQ, LuxS | AI-2 (furanosyl-borate diester?) | ? |
a
R-THMF, (2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahyrofuran.